Natsume's Book of Friends (2008)

The story takes place in an age where "Ajin" (demi-human), more casually known as "Demi," have slowly started to become accepted into human society. Tetsuo Takahashi is a biology teacher who ends up teaching three such Demi, hoping to understand more about them while also managing to catch their attention.

Hiyori Iki is a normal middle school student until she was involved in a bus accident while trying to protect a stranger. This incident causes her soul to frequently slip out of her body, and she becomes aware of the existence of two parallel worlds. Through her soul, she meets the strange, nameless god without a shrine, Yato. Yato is determined to make a name for himself out there by accepting any wishes for 5 yen, including Hiyori's to fix her body.

Arata Kaizaki (27) quit the job he landed after graduation in only three months. His life did not go well after that. Now his parents are threatening to stop sending money, and want him to come back to the country. He has no friend or girlfriend to share his troubles with...as he hits rock bottom a strange man named Ryou Yoake appears. He invites Arata to join a societal rehabilitation program for NEETs called ReLife. This program uses a mysterious drug to make him look younger, and sends him back to high school for a year...

She can see dead people…she just chooses to ignore them. That’s Miko’s plan, anyway, with horrifying (and sometimes hilarious) results.

For as long as he can remember, Ichigo Kurosaki has been able to see ghosts. But when he meets Rukia, a Soul Reaper who battles evil spirits known as Hollows, he finds his life is changed forever. Now, with a newfound wealth of spiritual energy, Ichigo discovers his true calling: to protect the living and the dead from evil.

Rather than take a more sensible approach to salvaging his grades in time for graduation, Alto summons a bit of otherworldly help. Only after does he learn he’s bound the legendary she-devil Vermeil into service as his familiar!

Shigeo Kageyama, a.k.a. "Mob," is a boy who has trouble expressing himself, but who happens to be a powerful esper. Mob is determined to live a normal life and keeps his ESP suppressed, but when his emotions surge to a level of 100%, something terrible happens to him! As he's surrounded by false espers, evil spirits, and mysterious organizations, what will Mob think? What choices will he make?

Fourteen-year-old Iruma Suzuki has just been abandoned and sold to a demon by his irresponsible parents! Surprisingly, the next thing he knows he's living with the demon who has adopted him as his new grandson and has been transferred into a school in the Netherworld where his new demon grandfather works as the principal. Thus begins the cowardly Iruma-kun's extraordinary school life among the otherworldly as he faces his true self, takes on challenges, and rises to become someone great.

Ginko, a Mushi master, travels from place to place researching the Mushi and helping people who are suffering because of it.

Koyomi Araragi, a high school student, finds himself constantly encountering girls afflicted by supernatural "oddities." He dedicates himself to helping them, often with the aid of the eccentric specialist Meme Oshino. Each arc talks about a different girl's unique struggle and the mysterious cause of their affliction. The series explores themes of adolescence, personal growth, and the complexities of human relationships. It's known for its witty dialogue, stylistic animation, and unique narrative structure.