Sherilyn Fenn, born Sheryl Ann Fenn on February 1, 1965, is an American actress best known for her iconic role as the seductive and complex Audrey Horne on the cult TV series Twin Peaks (1990–1991, 2017). She grew up in a musical family, traveling extensively before settling in Los Angeles, where she began acting with early B-movies like The Wild Life (1984), Thrashin' (1986), The Wraith (1986), and Two Moon Junction (1988).

In the early 1990s, Fenn's career breakthrough came with Twin Peaks, earning her an Emmy nomination for Outstanding Supporting Actress and a Golden Globe nomination. She credited acting coach Roy London with revitalizing her confidence, leading to roles in films like Wild at Heart (1990), Of Mice and Men (1992), Boxing Helena (1993), and the TV biopic Liz: The Elizabeth Taylor Story (1995).

Fenn later starred in the Showtime series Rude Awakening (1998–2001) as recovering addict Billie Frank, with recurring roles in S.W.A.T. (2017–2021) as Karen Street and Shining Vale (2021–). Recent films include Shooting Heroin (2020), Silent Life: The Story of the Lady in Black (2023), and Upon Waking (2023).