Josette Sheeran (born June 12, 1954) is an American diplomat, humanitarian, and businesswoman.

She served in the United States Department of State as Under Secretary of State for Secretary of State Condoleezza Rice covering Economic Growth, Energy, Technology, Agriculture and the Environment, with the rank of Ambassador. She served as Ambassador and Deputy U.S. Trade Representative under President George Bush, covering all Asia, Africa and Intellectual Property, Technology and Agriculture from 2001-2005.

She currently serves as founder and CEO of Firefly Global Group, a geopolitical and business consulting firm, supporting founders and accelerating new technologies which enhance national and human security.

Sheeran served as the seventh president and CEO of Asia Society from 2013 to 2020. Sheeran was also the United Nations's Special Envoy for Haiti, successfully leading efforts to end a devastating cholera epidemic there.