Laslo rose to fame in the 1980s and 1990s in the wake of comedy routines in which she portrayed such characters as 'Safta Zapta' and 'Clara the cleaning woman.' In 2005 she won the Best Actress Award at the 2005 Cannes Film Festival for her role in Free Zone.

Her parents were both Holocaust survivors. In 1972–1973, she served in the Israel Defense Forces Southern Command musical troupe. She was married to Israeli media proprietor Aviv Giladi, with whom she has two sons - Ben and Itamar. Her eldest, Ben Giladi, is a film producer that works for Len Blavatnik's AI-Film and operates between London, LA and Tel-Aviv. Her daughter-in-law is Israeli Actress Romi Aboulafia.

Hanna was also married and divorced businessman Benny Bloch.