Brandon Manderville was born Brandon Joseph Gorton in Brooklyn, New York to Joan Manderville and Brian Gorton. While growing up, Brandon joined his school's music and theatre programs, performing classical music or stage productions, respectively.

In March 2021, He founded Manderfilm, a Brooklyn-based Film Production and Post House. That same year, he joined the Tom Kane Theatre's Shakespeare ensemble.

When Brandon isn't on set acting, producing, or directing, he'll be on stage with his troupe, or in his studio composing for various films and commercials.