Siina Üksküla (until 1959 Zinaida Ignatenko; born June 16, 1938 in the village of Luiskovitsõ (Finnish: Luiskenitsa) in Jelizavetino village council, Krasnogvardeisk district, Leningrad region) is an Estonian actress.

She studied at the Viljandi Pioneers House ballet circle, graduated from Viljandi High School for Young Workers in 1957, and from the first year of the Performing Arts Department of the Tallinn State Conservatory in 1961.

She worked at the Rakvere Theater from 1961 to 1967 and at the Endla Theater from 1967 to 2000. Member of the Estonian Theater Association (1963) and honorary member of the Estonian Actors' Union.