Amy Rose Locane (born December 19, 1971) is an American convicted felon and former actress. She is best known for her role in John Waters' 1990 musical comedy Cry-Baby.

In September 2020, she began serving an eight-year sentence; she was convicted of killing a 60-year-old woman in a 2010 drunk driving crash. She was driving with a blood-alcohol level three times the legal limit during the June 27, 2010 crash, was cleared of the manslaughter charge but found guilty of vehicular homicide and assault by auto. She had previously been sentenced to three years in prison, of which she served two and a half, was released, and subsequently re-sentenced due to the leniency of the original sentence.