Nosipho Dumisa (born 1988) is a South African writer, director and producer. She co-founded the production company Gambit Films. She wrote and directed her first feature film, the crime thriller Nommer 37, first as a short in 2014, followed by a feature version in 2018. She created the Netflix series Blood & Water (2020). She previously worked as a producer on the Afrikaans soap opera Suidooster.

Her works have been premiered at South by Southwest and have won international awards. She has sat on the jury of the Neuchâtel International Fantastic Film Festival in Switzerland. Her works typically feature Cape Town, where she resides, as a setting.