Alexander was born in Vallejo, California and began working in the adult industry as a stripper in Sacramento when she was 18 to supplement her daytime earnings as a receptionist. She appeared in several adult magazines with her first photo shoot being with Earl Miller. She started performing in adult films in 2001 beginning with a girl-girl scene in Hot Showers Number and becoming a contract girl for Sin City in that year. In addition to a catalog of solely girl-girl hardcore work, she appeared in a handful of softcore erotic films produced by HBO and Cinemax such as Hotel Erotica, The Sex Spa, Sex House and Voyeur: Inside Out. She also became a solo and girl-girl internet nude model. Alexander appeared in a mainstream film titled Spider's Web with Stephen Baldwin in 2002. Monique makes a cameo appearance in the Season 3 finale of the HBO series Entourage.In 2007 she became a sports reporter on National Lampoon Comedy Radio's The Phil Show.

2002