Nana Natsume is a Japanese film actress, a former AV idol and a well-known celebrity in Japan.

Natsume was born on January 23, 1980 in Sakai, Osaka, Japan. After graduating from high school, she worked as a dental assistant and real estate saleswoman. She began her entertainment career with appearances in On Girls' File and Cure Sick Night, local late night television shows in Osaka. She was scouted for work in pornography in 2002. Moving to Tokyo, she appeared in photo features for several magazines including Shukan Gendai and Weekly Post. She was also featured in a photobook entitled 727 in July 2002 and in an "image" DVD called nana which was released in November 2002.

Natsume appeared for the Soft On Demand adult video company as the host of their AV Awards ceremony at Tokyo's Shinjuku Century Hyatt hotel on November 26, 2003. Her debut video, entitled simply Debut, was released in January, 2004. Sexually conservative and inexperienced, Natsume notes of her first video, "Just how embarrassed I look during the entire thing." She says her first experiences with both paizuri and masturbation occurred during AV shoots. One of her videos, Final Pussy!, released in January 2005 is notable for its science fiction theme. Directed by Noboru Iguchi, Natsume plays a dangerous woman who is the result of a military experiment gone wrong. When she is sexually aroused, guns burst from her breasts, killing her partner. Special makeup effects were by Yoshihiro Nishimura, well known in Japanese "gore" cinema.

In November 2005, she appeared in her first bukakke movie, Nana Natsume Showered by Semen directed by Kazuhiko Matsumoto, the man who is usually credited with inventing that genre of Japanese pornography. In December 2005 she did her video Stripper, a lesbian love story with former SOD star Kurumi Morishita, directed by ex-SOD director TOHJIRO.

Natsume has received recognition several times, from the media, the AV industry, and from fans. She received the Best AV Actress prize at the Tokyo Sports 5th annual Takeshi Kitano Awards in 2004. She won multiple awards at the 2005 SOD Awards, one for Best Actress and the SOD Grand Prize for contributions to company sales and image and she also was awarded the Best Actress prize at the 2006 SOD Awards. In addition, her video Face Within Japan, Body Within a Vehicle!! was given the Best Video prize at the 2006 AV Actress Grand Prix. She also earned mention in a Mainichi Shimbun story in 2006 by starring in Dirty DVD for Girls, a pornographic video targeted for women. The newspaper described Natsume as, "one of the biggest stick flick starlets in Japan."

Natsume remained with SOD for her entire career, usually making about one video a month. Her retirement video, released in October 2007, was an 8 disk, over 16 hour package with scenes chronicling her entire body of work from her debut. Tokyo gossip newspapers had previously reported Natsume's announcement that she would retire from the porn industry at the end of October 2007.