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Jericho, an aspiring doctor, seeks a mysterious alternative medicine in the provinces. The search unexpectedly brings him to Mang Donado, also known as Dr. Videoke, an owner of a videoke rental store. Upon arriving at Mang Donado's home, Jericho finds himself in an increasingly bizarre and unsettling situation involving Mang Donado's eerie antics and peculiar behavior. Desperation and curiosity drive Jericho to stay, leading to an unusual ritual that involves intense karaoke singing and the taking of natural plant-based psychedelics. As the search for this drug unfolds, Jericho is plunged into a surreal and unsettling experience that challenges his beliefs, pushing him to the brink of his sanity.
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Ren Amari is the driven inventor of a revolutionary new drug. OtherLife expands the brain's sense of time and creates virtual reality directly in the user's mind. With OtherLife, mere seconds in real life feel like hours or days of exciting adventures. As Ren and her colleagues race around the clock to launch OtherLife, the government muscles in to use the drugs as a radical solution to prison overcrowding. They will create virtual cells where criminals serve long sentences in just minutes of real time. When Ren resists, she finds herself an unwilling guinea pig trapped in a prison cell in her mind. She must escape before she descends into madness, and then regain control of OtherLife before others suffer the same fate.

Utah and his girlfriend Opal, are drug addicts living on the streets in rural Ohio. After getting recruited by body broker Wood and offered treatment in Los Angeles, Wood takes Utah under his wing and introduces him to treatment center mogul Vin. Wood and Vin bring Utah in on their lucrative and illegal dealings, where saving lives comes second to the bottom line.