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The story takes place in a mental hospital. Many things are going on. There is Pesta (Bucek Depp), a junky who was moved from a prison to the hospital. He meets Beth (Ine Febriyanti), the daughter of a high-ranking government official, who asked that her daughter gets a special treatment, but this must remain a secret. There are a poet, a politician and a nurse who was an ex-patient, and Beth’s helper, also Rehan (Nurul Arifin) who has her own set of problems. The doctors at the hospital seem no different from the patients. There is also an artist who makes installation art works. His artistic doctrin is: the more complicated it is for a work of art to be understood, the better. It is unclear if the artist is the hospital 's patient, because he is never inside of the hospital but is always in the courtyard.
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On the outside, Helen has it all – a loving family and a successful career – but when her suppressed mental illness resurfaces, the world crumbles around her. Crippled by depression, Helen finds solace through her friendship with Mathilda, a kindred spirit struggling with bipolar disorder.

Dr. Alan Stone breaks new ground for treatment of the mentally ill through an experiment on three paranoid schizophrenic patients who believe they are Jesus Christ.